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Non-injection treatments for arthritis in knee – Mayo Clinic Connect

I am looking for suggestions for treatments for arthritis knee pain that do not involve cortisone shots or gel shots (hyaluronic acid). Can anyone suggest a safe, effective hyaluronic supplement or topical cream instead? Are there any other completely non-invasive options? I have an issue with a heightened immune system that can become overstimulated and cause neuropathy problems. Thank you …